Gemcitabine is a drug used in chemotherapy for the treatment of several types of cancer. Our gemcitabine and derivate analysis provides fast and robust quantitative data.

Compounds Formula
Gemcitabine C9H11F2N3O4
dFdC, 2′,2′-difluoro 2′-deoxycytidine
dFdU C9H10F2N2O5
2′,2′-difluoro 2′- 2′-deoxyuridine
Gemcitabine-5-monophosphate C9H12F2N3O7P
dFdCMP
2′,2′-difluoro 2′-deoxycytidine monophosphate
Gemcitabine-5- diphosphate C9H14F2N3O10P2
dFdCDP
2′,2′-difluoro 2′-deoxycytidine diphosphate
Gemcitabine-5- triphosphate C9H14F2N3O13P3
dFdCTP
2′,2′-difluoro 2′-deoxycytidine triphosphate

 

Platform

  • LC-MS/MS

Summary

  • Identification and quantification of gemcitabine and derivates.

Sample Requirement

  • 100ul plasma; 50mg tissue; 5×10^6 cells

Reporting

  • A detailed report will be provided at the end of the project
  • Metabolites are reported as uM or ug/mg